Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes

dc.contributor.authorYeo, Adeline
dc.contributor.authorAzhar, Nur Atiqah
dc.contributor.authorYeow, Wanyi
dc.contributor.authorTalbot Jr., C. Conover
dc.contributor.authorAsif Khan, Mohammad
dc.contributor.authorShankar, Esaki M.
dc.contributor.authorRathakrishnan, Anusyah
dc.contributor.authorAzizan, Azliyati
dc.contributor.authorWang, Seok Mui
dc.contributor.authorKim Lee, Siew
dc.contributor.authorYik Fong, Mun Yik
dc.contributor.authorManikam, Rishya
dc.contributor.authorDevi Sekaran, Shamala
dc.date.accessioned2015-12-30T04:55:45Z
dc.date.available2015-12-30T04:55:45Z
dc.date.issued2014-04
dc.description.abstractDengue represents one of the most serious life-threatening vector-borne infectious diseases that afflicts approximately 50 million people across the globe annually. Whilst symptomatic infections are frequently reported, asymptomatic dengue remains largely unnoticed. Therefore, we sought to investigate the immune correlates conferring protection to individuals that remain clinically asymptomatic.
dc.identifier.citationYeo, A. S., Azhar, N. A., Yeow, W., Talbot Jr, C. C., Khan, M. A., Shankar, E. M., ... & Sekaran, S. D. (2014). Lack of clinical manifestations in asymptomatic dengue infection is attributed to broad down-regulation and selective up-regulation of host defence response genes. PloS one, 9(4), e92240. doi:10.1371/journal.pone.0092240
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/983
dc.language.isoen
dc.publisherPLOS ONE:Open Access journal
dc.rightsOpen access
dc.subjectclinical manifestations
dc.subjectasymptomatic dengue
dc.subjectgene expression
dc.titleLack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes
dc.typeArticle

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