Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia

Simple item page
dc.contributor.authorD. Poddighe
dc.contributor.authorAida Turganbekova
dc.contributor.authorDana Baymukasheva
dc.contributor.authorZhazira Saduakas
dc.contributor.authorZhuldyz Zhanzakova
dc.contributor.authorSaniya Abdrakhmanova
dc.date.accessioned2025-08-19T12:39:45Z
dc.date.available2025-08-19T12:39:45Z
dc.date.issued2020-01-01
dc.description.abstractThis study analyzed HLA-DQ genotypes of healthy bone marrow donors from Kazakhstan’s national registry and found that the frequency of celiac disease–related alleles (HLA-DQB1 variants) is significant and comparable to Western countries. Given the wheat-based dietary patterns in Kazakhstan, these results suggest that celiac disease prevalence may be higher than assumed, underscoring the need for cost-effective diagnostic strategies in Central Asia. en
dc.identifier.citationPoddighe D, Turganbekova A, Baymukasheva D, Saduakas Z, Zhanzakova Z, Abdrakhmanova S (2020). Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia. PLoS ONE, 15(1):e0226546. doi:10.1371/journal.pone.0226546 en
dc.identifier.doi10.1371/journal.pone.0226546
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0226546
dc.identifier.urihttps://nur.nu.edu.kz/handle/123456789/9619
dc.language.isoen
dc.publisherPublic Library of Science
dc.relation.ispartofPLOS ONEen
dc.rightsOpen accessen
dc.sourcePLOS ONE, 15(1), e0226546, (2020)en
dc.subjectceliac disease, HLA-DQ2, HLA-DQ8, genetic predisposition, Kazakhstan, bone marrow donors, diagnostic strategiesen
dc.titleGenetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asiaen
dc.typeJournal Articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Genetic_predisposition_to_celiac_disease_in_Kazakhstan__Potential_impact_on_the_clinical_practice_in_Central_Asia__95c8c29c.pdf
Size:
378.69 KB
Format:
Adobe Portable Document Format
Download

Collections

Articles