Epigenetic reprogramming of cancer cells under embryonic microenvironment

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dc.contributor.authorMu, X.
dc.contributor.authorSultankulov, B.
dc.contributor.authorAgarwal, R.
dc.contributor.authorMahjoub, A.
dc.contributor.authorSchott, T.
dc.contributor.authorGreco, N.
dc.contributor.authorHuard, J.
dc.contributor.authorWeiss, K.
dc.date.accessioned2015-10-26T10:03:44Z
dc.date.available2015-10-26T10:03:44Z
dc.date.issued2014
dc.description.abstractThe idea of epigenetic reprogramming of cancer cells by an embryonic microenvironment possesses potential interest from the prospect of both basic science and potential therapeutic strategies. Chick embryo extract (CEE) has been used for the successful expansion of many specific stem cells and has demonstrated the ability to facilitate DNA demethylation. The current study was conducted to compare the status of DNA methylation in highly metastatic and less metastatic osteosarcoma cells and to investigate whether CEE may affect the epigenetic regulation of tumor suppressor genes and thus change the metastatic phenotypes of highly metastatic osteosarcoma cells.ru_RU
dc.identifier.isbn9786018046728
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/466
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectepigenetic reprogrammingru_RU
dc.subjectembryonic microenvironmentru_RU
dc.subjectosteosarcoma cellsru_RU
dc.subjectcell apoptosisru_RU
dc.subjectgenesru_RU
dc.titleEpigenetic reprogramming of cancer cells under embryonic microenvironmentru_RU
dc.typeAbstractru_RU

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