Traditional Risk Factors of Acute Coronary Syndrome in Four Different Male Populations – Total Cholesterol Value Does Not Seem To Be Relevant Risk Factor

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dc.contributor.authorHubacek, J. A.
dc.contributor.authorStanek, V.
dc.contributor.authorGebauerova, M.
dc.contributor.authorAdamkova, V.
dc.contributor.authorLesauskaite, V.
dc.contributor.authorZaliaduonyte-Peksiene, D.
dc.contributor.authorTamosiunas, A.
dc.contributor.authorSupiyev, A.
dc.contributor.authorKossumov, A.
dc.contributor.authorZhumadilova, A.
dc.contributor.authorPitha, J.
dc.date.accessioned2017-11-07T10:36:16Z
dc.date.available2017-11-07T10:36:16Z
dc.date.issued2017-01-09
dc.description.abstractCardiovascular diseases are the most common cause of mortality and morbidity in most populations. As the traditional modifiable risk factors (smoking, hypertension, dyslipidemia, diabetes mellitus, and obesity) were defined decades ago, we decided to analyze recent data in patients who survived acute coronary syndrome (ACS). The Czech part of the study included data from 999 males, and compared them with the post-MONICA study(1,259 males, representing general population). The Lithuanianstudy included 479 male patients and 456 age-matched controls. The Kazakhstan part included 232 patients and 413 controls.In two countries, the most robust ACS risk factor was smoking (OR 3.85 in the Czech study and 5.76 in the Lithuanian study), followed by diabetes (OR 2.26 and 2.07) and hypertension (moderate risk elevation with OR 1.43 and 1.49). These factors did not influence the ACS risk in Kazakhstan. BMI had no significant effect on ACS and plasma cholesterol was surprisingly significantly lower (P<0.001) in patients than in controls in all countries (4.80±1.11 vs. 5.76±1.06 mmol/l in Czechs; 5.32±1.32 vs. 5.71±1.08 mmol/l in Lithuanians; 4.88±1.05 vs. 5.38±1.13 mmol/l in Kazakhs/Russians). Results from our study indicate substantial heterogeneity regarding major CVD risk factors in different populations with the exception of plasma total cholesterol which was inversely associated with ACS risk in all involved groups. These data reflect ethnical and geographical differences as well as changing pattern of cardiovascular risk profiles.ru_RU
dc.identifier.citationHubacek J. A. et al.(>10), 2017(January 9), Traditional Risk Factors of Acute Coronary Syndrome in Four Different Male Populations – Total Cholesterol Value Does Not Seem To Be Relevant Risk Factor, Physiological research, vol.66ru_RU
dc.identifier.issn0862-8408 (print)
dc.identifier.issn1802-9973 (online)
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/2746
dc.language.isoenru_RU
dc.publisherPhysiological researchru_RU
dc.rightsOpen Access - the content is available to the general publicru_RU
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectacute coronary syndromeru_RU
dc.subjectObesityru_RU
dc.subjectHypertensionru_RU
dc.subjectCholesterolru_RU
dc.subjectDiabetesru_RU
dc.subjectSmokingru_RU
dc.subjectPrevalenceru_RU
dc.titleTraditional Risk Factors of Acute Coronary Syndrome in Four Different Male Populations – Total Cholesterol Value Does Not Seem To Be Relevant Risk Factorru_RU
dc.typeArticleru_RU

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