RISK FACTORS FOR POSTOPERATIVE OSTEOMYELITIS AMONG PATIENTS AFTER BONE FRACTURE: A MATCHED CASE–CONTROL STUDY
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Date
2022
Authors
Slyamova, Gulnur
Gusmanov, Arnur
Batpenov, Arman
Kaliev, Nurlan
Viderman, Dmitriy
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of Clinical Medicine
Abstract
The healthcare burden of osteomyelitis is increasing. Postoperative and posttraumatic
osteomyelitis account for 80% of all cases of osteomyelitis. The aim of this study was to find
risk factors for postoperative osteomyelitis in Kazakhstan. We included 245 patients admitted to
the National Scientific Center of Traumatology and Orthopedics from 2018 to 2020. Cases were
matched with controls in a 1:4 ratio. Exact matching was performed by gender, ICD-10, and ICD-9
codes. The main variables included socio-demographics, diagnosis at admission, characteristics of
fractures, comorbidities, complications, hospitalization milestones, and osteomyelitis characteristics.
Descriptive analyses, along with bivariate analysis and multivariate conditional logistic regression,
were performed. Open fracture (adjOR = 6.25; 95%CI 1.64–23.79), the presence of complications of
initial fracture (adjOR = 3.46, 95%CI 1.13–10.56), comminuted fracture form (adjOR = 1.87; 95%CI
0.73–4.75), a positive history of diabetes or blood glucose >7 g/L (adjOR = 4.25; 95%CI 1.26–14.3),
incision or wound length of more than 10 cm (adjOR = 6.53; 95%CI 1.1–38.6), additional implanted
medical item (adjOR = 1.23; 95% CI 1.1–1.47), and unemployment or being retired (adjOR = 4.21;
95%CI 1.74–10.18) were found to be significant predictors of postoperative osteomyelitis. Almost all
our findings are concordant with previous studies, except for the type of fracture. Different authors
report conflicting results on the latter potential risk factor. Therefore, prospective studies on this issue
are required.
Description
Keywords
Type of access: Open Access, osteomyelitis, risk factors, postoperative complications, infection, outcomes
Citation
Slyamova, G., Gusmanov, A., Batpenov, A., Kaliev, N., & Viderman, D. (2022). Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study. Journal of Clinical Medicine, 11(20), 6072. https://doi.org/10.3390/jcm11206072