Rage targeted strategies for Alzheimer`s Amyloid B peptide include blood brain barrier dysfunctions

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dc.contributor.authorAskarova, Sholpan
dc.contributor.authorTsoy, A.
dc.contributor.authorLee, J.C-M.
dc.date.accessioned2015-10-27T05:48:07Z
dc.date.available2015-10-27T05:48:07Z
dc.date.issued2013
dc.description.abstractThis study demonstrated that Aβ binding to RAGE at the CECs and astrocytes surface is required for NADPH oxidase complex assembling, resulting in subsequent ROS generation and phosphorylation of cPLA2α. Therefore, understanding precise molecular mechanisms underlying Aβ mediated oxidative damage may provide new insights into the development of preventive and treatment strategies for AD.ru_RU
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/504
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectAlzheimer’s diseaseru_RU
dc.subjecthealthcare systemru_RU
dc.titleRage targeted strategies for Alzheimer`s Amyloid B peptide include blood brain barrier dysfunctionsru_RU
dc.typeAbstractru_RU

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