AN ENZYME-TRIGGERED CROSS LINKING APPROACH FOR SHAPE 3D-PRINTING OF CELL-LADEN SCAFFOLDS FOR AN ADVANCED BONE TISSUE REGENERATION

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dc.contributor.authorYernaimanova, Bota
dc.date.accessioned2024-06-23T20:23:07Z
dc.date.available2024-06-23T20:23:07Z
dc.date.issued2024-04-23
dc.description.abstractVarious pathologies contribute to the occurrence of bone defects - from osteoporosis and cancer to reconstructive surgeries, congenital deformities, and traumatic injuries. Despite the advantages of auto-, allo- and other bone grafts, in clinical practice, they face many limitations such as donor site morbidity, incompatibility with native tissue, etc. Regenerative bioengineering today offers innovative approaches using engineered materials, including soft and hard biomaterials that closely mimic the extracellular matrix's (ECM) structure. In this work, a new biomaterial suitable for extrusion 3D bioprinting is introduced. The advantages are that it meets the criteria for bone defect treatment, namely pore interconnectivity and porosity (d > 150 µm), biodegradability, and biocompatibility due to enzymatic crosslinking.en_US
dc.identifier.citationYernaimanova, B. (2024). An Enzyme-Triggered Cross Linking Approach for Shape 3D-Printing of Cell-Laden Scaffolds for an Advanced Bone Tissue Regeneration. Nazarbayev University School of Engineering and Digital Sciencesen_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/7974
dc.language.isoenen_US
dc.publisherNazarbayev University School of Engineering and Digital Sciencesen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subject3D bioprintingen_US
dc.subjectEnzymatic crosslinkingen_US
dc.subjectTissue engineeringen_US
dc.subjectType of access: Restricteden_US
dc.titleAN ENZYME-TRIGGERED CROSS LINKING APPROACH FOR SHAPE 3D-PRINTING OF CELL-LADEN SCAFFOLDS FOR AN ADVANCED BONE TISSUE REGENERATIONen_US
dc.typeMaster's thesisen_US
workflow.import.sourcescience

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