PEDIATRIC ULCERATIVE COLITIS IN KAZAKHSTAN: FIRST CASE SERIES FROM CENTRAL ASIA AND CURRENT CLINICAL MANAGEMENT
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Date
2020-11-14
Authors
Poddighe, Dimitri
Telman, Aigerim
Tuleutayev, Ernas
Ibrayeva, Aigul
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Abstract
The diagnoses of ulcerative colitis have increased in pediatric patients in the last two
decades. Whereas there are several reports from most areas of the world, no clinical studies describing
the clinical management of pediatric ulcerative colitis are currently available from Central Asia.
In this article, we first describe a case series of pediatric patients affected with ulcerative colitis in
Kazakhstan. This is a retrospective study including 25 consecutive pediatric patients diagnosed with
ulcerative colitis in a tertiary pediatric hospital. The available demographic, clinical, hematological
and inflammatory parameters at diagnosis and at the first one-year follow-up have been provided
and analyzed. Most pediatric patients diagnosed with ulcerative colitis were older than 12 years,
with prevalence of male gender. The analysis of clinical, laboratory, endoscopic parameters at
the diagnosis suggested a significant diagnostic delay compared to developed countries; however,
most of them showed clinical, laboratory and endoscopic improvements at the one-year follow-up.
Even though the therapeutic approach and outcomes resulted to be consistent with other clinical
studies from developed countries, several aspects of the medical follow-up should be improved,
especially in pediatric patients with extensive disease.
Description
Keywords
ulcerative colitis, pediatric inflammatory bowel diseases, Kazakhstan, Central Asia, body mass index (BMI), anemia, medical monitoring, eosinophils, pediatric gastroenterology, BMI, body mass index, Research Subject Categories::MEDICINE
Citation
Poddighe, D., Telman, A., Tuleutayev, E., & Ibrayeva, A. (2020). Pediatric Ulcerative Colitis in Kazakhstan: First Case Series from Central Asia and Current Clinical Management. Gastroenterology Insights, 11(2), 27–35. https://doi.org/10.3390/gastroent11020006