Seroprevalences of autoantibodies and anti-infectious antibodies among Ghana’s healthy population

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dc.contributor.authorItai Katz
dc.contributor.authorF. De Luca
dc.contributor.authorBartholomew Dzudzor
dc.contributor.authorB. Kyei Sarpong
dc.contributor.authorBeatrice Osei-…
dc.date.accessioned2025-08-20T04:04:55Z
dc.date.available2025-08-20T04:04:55Z
dc.date.issued2020-01-01
dc.description.abstractThis study assessed the seroprevalence of a range of autoantibodies and anti-infectious antibodies in healthy individuals from four regions of Ghana. High prevalence was found for anti‑HSV‑1 IgG (91‑100%), anti‑EBNA IgG (81‑93%), and anti‑EBV‑VCA IgG (97‑100%). ANA positivity was estimated at 14%, and anti‑dsDNA at 2.3%. After adjusting for age, gender, region, and family history, an inverse association between anti‑HSV‑2 antibodies and ANA was observed (adjusted OR = 0.398; p = 0.044), suggesting a potential protective effect of HSV‑2 against autoimmunity. A similar, non‑significant trend was noted for anti‑dsDNA antibodies (p = 0.1)., en
dc.identifier.citationKatz, I.; De Luca, F.; Dzudzor, B.; Kyei Sarpong, B.; Osei-… (2020). Sci. Rep., 10:2814. https://doi.org/10.1038/s41598-020-59693-xen
dc.identifier.doi10.1038/s41598-020-59693-x
dc.identifier.urihttps://doi.org/10.1038/s41598-020-59693-x
dc.identifier.urihttps://nur.nu.edu.kz/handle/123456789/9663
dc.language.isoen
dc.publisherNature Portfolio
dc.relation.ispartofScientific Reportsen
dc.rightsOpen accessen
dc.sourceScientific Reports, 10, 2814, (2020)en
dc.subjectseroprevalenceen
dc.subjectautoantibodiesen
dc.subjectinfectious antibodiesen
dc.subjectGhanaen
dc.titleSeroprevalences of autoantibodies and anti-infectious antibodies among Ghana’s healthy populationen
dc.typeJournal Articleen

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