Individual screening strategy for pediatric celiac disease

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dc.contributor.authorDimitri Poddighe
dc.date.accessioned2025-08-06T10:39:15Z
dc.date.available2025-08-06T10:39:15Z
dc.date.issued2018
dc.description.abstractIn this letter, Poddighe comments on the high (≈15%) prevalence of celiac disease (CD) found in first‑degree relatives (FDRs) of pediatric CD index cases, especially in children under 10 years. He advocates for an individualized screening strategy targeting pediatric FDRs to enable early diagnosis and mitigate growth and developmental issues. The author highlights that most CD children are carriers of the HLA‑DQB1*02:01 allele (around 90%), suggesting HLA genotyping could inform cost-effective screening protocols.
dc.identifier.citationoddighe, D. (2018). Individual screening strategy for pediatric celiac disease. European Journal of Pediatrics, 177(12), 1871. DOI: 10.1007/s00431-018-3251-6
dc.identifier.urihttps://nur.nu.edu.kz/handle/123456789/9098
dc.language.isoen
dc.subjectpediatric celiac disease
dc.subjectindividual screening strategy
dc.subjectfirst-degree relatives
dc.subjectHLA-DQ2/DQB1
dc.subjectcost-effective screening
dc.titleIndividual screening strategy for pediatric celiac disease
dc.typeArticle

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