AB060. Autophagy-associated biomarkers ULK2, UVRAG, and miRNAs miR-21, miR-126, and miR-374: prognostic significance in glioma patients

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dc.contributor.authorWajiha Amin
dc.contributor.authorSyed Hani Abidi
dc.contributor.authorSufiyan Sufiyan
dc.contributor.authorSahar Ilyas
dc.contributor.authorSana Naeem
dc.contributor.authorSiraj Uddin
dc.contributor.authorSyed Ather Enam
dc.contributor.authorNouman Mughal
dc.date.accessioned2025-08-26T08:38:59Z
dc.date.available2025-08-26T08:38:59Z
dc.date.issued2024-08-01
dc.description.abstractAutophagy is a self-renewing process of the cell having a dual role in gliomagenesis depending on the tumor stage. Several microRNAs play a key role in the regulation of autophagy and the outcome of cancer. We investigated the potential relevance of autophagy in gliomagenesis and survival by exploring the association of the basal gene expression of autophagy-associated markers LC3, ULK1/2, UVRAG, Beclin1, mTOR, UVRAG, PI3K, AKT, PTEN and their target microRNAs miR-126, miR-374, miR-21, miR-7, miR-204 and miR-100 in low- and high-grades of gliomas.en
dc.identifier.citationAmin Wajiha, Abidi Syed Hani, Sufiyan Sufiyan, Ilyas Sahar, Naeem Sana, Uddin Siraj, Enam Syed Ather, Mughal Nouman. (2024). AB060. Autophagy-associated biomarkers ULK2, UVRAG, and miRNAs miR-21, miR-126, and miR-374: prognostic significance in glioma patients. Chinese Clinical Oncology. https://doi.org/https://doi.org/10.21037/cco-24-ab060en
dc.identifier.doi10.21037/cco-24-ab060
dc.identifier.urihttps://doi.org/10.21037/cco-24-ab060
dc.identifier.urihttps://nur.nu.edu.kz/handle/123456789/10088
dc.language.isoen
dc.publisherAME Publishing Company
dc.relation.ispartofChinese Clinical Oncologyen
dc.sourceChinese Clinical Oncology, (2024)en
dc.subjectAutophagyen
dc.subjectMedicineen
dc.subjectGliomaen
dc.subjectmicroRNAen
dc.subjectCancer researchen
dc.subjectClinical significanceen
dc.subjectPathologyen
dc.subjectBiologyen
dc.subjectGeneen
dc.subjectGeneticsen
dc.subjectApoptosisen
dc.subjecttype of access: open accessen
dc.titleAB060. Autophagy-associated biomarkers ULK2, UVRAG, and miRNAs miR-21, miR-126, and miR-374: prognostic significance in glioma patientsen
dc.typearticleen

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