HLA-DRB1 AND –DQB1 ALLELES, HAPLOTYPES AND GENOTYPES IN EMIRATI PATIENTS WITH TYPE 1 DIABETES UNDERSCORES THE BENEFITS OF EVALUATING UNDERSTUDIED POPULATIONS
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Authors
Yafei, Zain Al
Mack, Steven J.
Alvares, Marion
Ali, Bassam R.
Afandi, Bachar
Beshyah, Salem A.
Sharma, Charu
Osman, Wael
Mirghani, Rajaa
Nasr, Amre
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Frontiers in Genetics
Abstract
HLA class II (DR and DQ) alleles and antigens have historically shown strong
genetic predisposition to type 1 diabetes (T1D). This study evaluated the association of
DRB1 and DQB1 alleles, genotypes, and haplotypes with T1D in United Arab Emirates
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al Yafei, Z., Mack, S. J., Alvares, M., Ali, B. R., Afandi, B., Beshyah, S. A., Sharma, C., Osman, W., Mirghani, R., Nasr, A., al Remithi, S., al Jubeh, J., Almawi, W. Y., AlKaabi, J., & ElGhazali, G. (2022). HLA-DRB1 and –DQB1 Alleles, Haplotypes and Genotypes in Emirati Patients with Type 1 Diabetes Underscores the Benefits of Evaluating Understudied Populations. Frontiers in Genetics, 13. https://doi.org/10.3389/fgene.2022.841879
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