Molecular epidemiology of HIV-1 subtype A in former Soviet Union countries

Simple item page
dc.contributor.authorAibekova, Lazzat
dc.contributor.authorFoley, Brian
dc.contributor.authorHortelano, Gonzalo
dc.contributor.authorRaees, Muhammad
dc.contributor.authorAbdraimov, Sabit
dc.contributor.authorToichuev, Rakhmanbek
dc.contributor.authorAli, Syed
dc.contributor.editorSandstrom, Paul
dc.date.accessioned2019-03-26T06:50:23Z
dc.date.available2019-03-26T06:50:23Z
dc.date.issued2018-02-01
dc.description.abstractWhile in other parts of the world it is on decline, incidence of HIV infection continues to rise in the former Soviet Union (FSU) countries. The present study was conducted to investigate the patterns and modes of HIV transmission in FSU countries. We performed phylogenetic analysis of publicly available 2705 HIV-1 subtype A pol sequences from thirteen FSU countries: Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kazakhstan, Kyrgyzstan, Latvia, Lithuania, Moldova, Russia, Ukraine and Uzbekistan. Our analysis showed that the clusters from FSU countries were intermixed, indicating a possible role of transmigration in HIV transmission. Injection drug use was found to be the most frequent mode of transmission, while the clusters from PWID and heterosexual transmission were intermixed, indicating bridging of HIV infection across populations. To control the expanding HIV epidemic in this region, harm reduction strategies should be focused on three modes of transmission, namely, cross-border migration, injection drug use and heterosexual.en_US
dc.identifier.citationAibekova L, Foley B, Hortelano G, Raees M, Abdraimov S, Toichuev R, et al. (2018) Molecular epidemiology of HIV-1 subtype A in former Soviet Union countries. PLoS ONE 13(2): e0191891. https://doi.org/10.1371/journal. pone.0191891en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/3793
dc.language.isoenen_US
dc.publisherPLoS ONEen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.titleMolecular epidemiology of HIV-1 subtype A in former Soviet Union countriesen_US
dc.typeArticleen_US
workflow.import.sourcescience

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
journal.pone.0191891.pdf
Size:
2.46 MB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
6 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Articles