Biomarkers, interventions and healthy ageing

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dc.contributor.authorKenessary, Almas
dc.contributor.authorZhumadilov, Zhaxybay
dc.contributor.authorNurgozhin, Talgat
dc.contributor.authorKipling, David
dc.contributor.authorYeoman, Mark
dc.contributor.authorCox, Lynne
dc.contributor.authorOstler, Elizabeth
dc.contributor.authorFaragher, Richard
dc.creatorAlmas, Kenessary
dc.date.accessioned2017-12-22T03:55:23Z
dc.date.available2017-12-22T03:55:23Z
dc.date.issued2013-05-25
dc.description.abstractPopulation ageing is probably the single most important healthcare challenge the developed and developing world will face in the 21st century. This is because the later part of the human life course is marked by the emergence of a wide spectrum of pathological impairments which increase morbidity and reduce quality of life. The processes driving these increases in mortality and morbidity are often conceptualised as highly complex and multi-causal. Indeed, it has been suggested that there is no human ‘ageing process’, only distinct, disease-specific mechanisms of pathology.However, humans are not the only organisms within the biosphere to show ageing and the use of cross-species approaches has demonstrated that common ageing processes exist and allowed some of the common genetic pathways controlling them to be identified. Mutants in these pathways either delay or accelerate the development of late life diseases giving rise to extended healthy lives or progerias, respectively. These advances in fundamental understanding open opportunities for a more detailed investigation of the key causal mechanisms underlying ageing and the exploitation of that knowledge for improved interventions in later life.en_US
dc.identifierDOI:10.1016/j.nbt.2012.11.018
dc.identifier.citationAlmas Kenessary, Zhaxybay Zhumadilov, Talgat Nurgozhin, David Kipling, Mark Yeoman, Lynne Cox, Elizabeth Ostler, Richard Faragher, Biomarkers, interventions and healthy ageing, In New Biotechnology, Volume 30, Issue 4, 2013, Pages 373-377en_US
dc.identifier.issn18716784
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1871678412008758
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/3023
dc.language.isoenen_US
dc.publisherNew Biotechnologyen_US
dc.relation.ispartofNew Biotechnology
dc.rights.licenseCopyright © 2012 Elsevier B.V. All rights reserved.
dc.titleBiomarkers, interventions and healthy ageingen_US
dc.typeArticleen_US
elsevier.aggregationtypeJournal
elsevier.coverdate2013-05-25
elsevier.coverdisplaydate25 May 2013
elsevier.endingpage377
elsevier.identifier.doi10.1016/j.nbt.2012.11.018
elsevier.identifier.eid1-s2.0-S1871678412008758
elsevier.identifier.piiS1871-6784(12)00875-8
elsevier.identifier.pubmedid23201073
elsevier.identifier.scopusid84877832564
elsevier.issue.identifier4
elsevier.issue.nameSpecial Issue: 15th European Congress on Biotechnology (ECB15), Istanbul, 23-26th September 2012
elsevier.openaccess0
elsevier.openaccessarticlefalse
elsevier.openarchivearticlefalse
elsevier.startingpage373
elsevier.teaserPopulation ageing is probably the single most important healthcare challenge the developed and developing world will face in the 21st century. This is because the later part of the human life course...
elsevier.volume30
workflow.import.sourcescience

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