New serum biomarker for rheumatoid arthritis

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dc.contributor.authorMyngbay, A.
dc.contributor.authorAdilbayeva, A.
dc.contributor.authorAdarichev, V. A.
dc.date.accessioned2015-10-22T10:05:37Z
dc.date.available2015-10-22T10:05:37Z
dc.date.issued2014
dc.description.abstractDevelopment of hypercellular invasive pannus tissue within synovial joints is a hallmark of Rheumatoid Arthritis (RA). Pannus produces proteases that damage bone and cartilage. Non-invasive monitoring of pannus activity is important for clinical assessment of patients as well as for control of the efficacy of therapeutic interventions. Available biomarkers are not satisfactory in terms of pannus specificity and sensitivity for monitoring local inflammation and bone erosion. Our goal is collecting clinical samples of synovial fluid and plasma from patients with RA and/or osteoarthritis (OA) to study the role of WNT signaling in pannus formation and developing set of serum biomarkers to monitor pannus activity.ru_RU
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/417
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectserumru_RU
dc.subjectbiomarkerru_RU
dc.subjectrheumatoid arthritisru_RU
dc.subjectproteinru_RU
dc.subjectblood plasmaru_RU
dc.titleNew serum biomarker for rheumatoid arthritisru_RU
dc.typeAbstractru_RU

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