Editorial: CCR5: A receptor at the center stage in infection

Abstract

This editorial highlights the pivotal role of the chemokine receptor CCR5 in the context of infectious diseases. CCR5 has long been studied for its involvement in HIV pathogenesis, but emerging research demonstrates its broader significance in viral, bacterial, and inflammatory responses. The editorial introduces contributions that examine CCR5’s regulatory functions in immune cell trafficking, tissue inflammation, and therapeutic targeting. These studies provide new insights into the receptor’s dual role as a pathogen entry point and an immune modulator, suggesting novel avenues for vaccine and drug development.