Migration characteristics of cell grown in embryonic microenvironment and under antiviral agents
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Date
2016-05
Authors
Karapina, O.
Shaimerdenova, M.
Mektepbayeva, D.
Akilbekova, D.
Journal Title
Journal ISSN
Volume Title
Publisher
National Laboratory Astana, NAZARBAYEV UNIVERSITY
Abstract
Cancer metastasis is a crucial process of spread of cancer cells from the origin
of tumor lesion to the tissues and other organs beyond, where new tumor lesions are formed which might be a single kick of event that may bring to the death of most of cancer suffering
patients. It is known that there are various characteristics between aggressive cancer cells
and embryonic progenitors, which gave rise to the theory of "embryonic rest" and suggested
possibility of presence of dormant embryonic remnants in differentiated tissues that may
have direct link to the generation of cancer lesions when these remnants get activated in the
differentiated tissue microenvironments. This concept was a foundation to use of embryonic
microenvironment as a treating agent against cancer cells. There are many factors like bad
died, use of tobacco, genetic factors and viral infections that influence the occurrence of cancer.
It is well-known that cancer cells have a long history with viruses, which may give arise to
cancer lesions. It is estimated that 15 percent of all worldwide human cancer cases are related
to viruses, which represents a major portion of worldwide cancer problems. Thus, it was decided
to use of antiviral agent (e.g. Acyclovir) as well as with chicken embryonic extract in cancer cell
reprogramming
Description
Keywords
Cancer, cancer cells, embryonic microenvironment, viruses, migration, proliferation
Citation
O. Karapina, M. Shaimerdenova, D. Mektepbayeva, and D. Akilbekova. 2016. Migration characteristics of cell grown in embryonic microenvironment and under antiviral agents. Abstract book. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1538