SYNTHESIS OF MORPHOLINES THROUGH THE PPH3- CATALYZED POST-UGI INTRAMOLECULAR UMPOLUNG OXA MICHAEL ADDITION

Abstract

One of the main directions in the development of modern organic chemistry is to increase the efficiency of the synthesis of complex structures. The goal of organic synthesis is not only to obtain target compounds, but also to develop methodologies with the lowest cost and minimum harm to the environment. At the present time, multicomponent reactions that are based on the idea of mixing of more than two starting reagents are of particular interest. Their main advantage is that they provide the ability to create fully convergent synthetic strategies with a minimum number of steps...