Bacterial growth in media mimicking the high salt and alkalinity of extreme kazakhstan environments results in production of antimicrobial compounds in soil actinomycetes isolated from these extremophile locations
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Date
2013-04-13
Authors
Roberts, Jill
Trenozhnikova, Lyudmila
Seaton, Lylah
Patel, Ami
Faza, Colton
Whitaker, Jacqueline
Mayer, Christen
Azizan, Azliyati
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of Pharmaceutical Technology & Drug Research
Abstract
Increasing antibiotic resistance among multidrug resistant pathogens necessitates the search for newer antimicrobials. Streptomyces historically produce the largest number of antibacterials and herein we describe isolation of antagonists from extremophiles using unusual culture media. Antagonists or antimicrobials produced under extremophile environmental conditions demonstrated activity against MRSA from Kazakhstan and the United States.
Description
Keywords
Streptomyces, Extremophiles, antagonists, antibacterial, antibiotics, HA-MRSA, Research Subject Categories::MEDICINE