Morphometric characteristics of cancer cells grown in embryonic microenvironment and under antiviral treatment

Abstract

Aggressive cancer cells express markers of multipotent stem cells and tightly interconnect with its surrounding microenvironment, by which the differential plasticity of cancer cells and also its carcinogenicity is regulated. Based on the fact that both cancer cells and stem cell use the same signaling molecules for self-renewal and differentiation, it is hypothesized that embryonic microenvironment, which is modulated by stem cells and is essential for stem cells differentiation, can be used for changing the morphometric characteristics of cancer cells and as a result lead to reprogramming of aggressive cancer cells malignant phenotype into more benign phenotype. The same is stated regarding antiviral agent, which is shown to change morphological characteristics and properties of malignant phenotype of cancer cells.