GALACTOSE-INDUCED SKIN AGING: THE ROLE OF OXIDATIVE STRESS

Simple item page
dc.contributor.authorUmbayev, Bauyrzhan
dc.contributor.authorAskarova, Sholpan
dc.contributor.authorAlmabayeva, Aigul
dc.contributor.authorSaliev, Timur
dc.contributor.authorMasoud, Abdul-Razak
dc.contributor.authorBulanin, Denis
dc.date.accessioned2021-07-08T04:38:56Z
dc.date.available2021-07-08T04:38:56Z
dc.date.issued2020-06-17
dc.description.abstractSkin aging has been associated with a higher dietary intake of carbohydrates, particularly glucose and galactose. In fact, the carbohydrates are capable of damaging the skin’s vital components through nonenzymatic glycation, the covalent attachment of sugar to a protein, and subsequent production of advanced glycation end products (AGEs). This review is focused on the role of D-galactose in the development of skin aging and its relation to oxidative stress. The interest in this problem was dictated by recent findings that used in vitro and in vivo models. The review highlights the recent advances in the underlying molecular mechanisms of D-galactose-mediated cell senescence and cytotoxicity. We have also proposed the possible impact of galactosemia on skin aging and its clinical relevance. The understanding of molecular mechanisms of skin aging mediated by D-galactose can help dermatologists optimize methods for prevention and treatment of skin senescence and aging-related skin diseases.en_US
dc.identifier.citationUmbayev, B., Askarova, S., Almabayeva, A., Saliev, T., Masoud, A.-R., & Bulanin, D. (2020). Galactose-Induced Skin Aging: The Role of Oxidative Stress. Oxidative Medicine and Cellular Longevity, 2020, 1–15. https://doi.org/10.1155/2020/7145656en_US
dc.identifier.issn1942-0900
dc.identifier.urihttps://doi.org/10.1155/2020/7145656
dc.identifier.urihttps://www.hindawi.com/journals/omcl/2020/7145656/
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/5531
dc.language.isoenen_US
dc.publisherHindawien_US
dc.relation.ispartofseriesOxidative Medicine and Cellular Longevity;Volume 2020, Article ID 7145656, 15 pages
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectadvanced glycation end productsen_US
dc.subjectAGEsen_US
dc.subjectagingen_US
dc.subjectskin agingen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.subjectType of access: Open Accessen_US
dc.subjectoxidative stressen_US
dc.titleGALACTOSE-INDUCED SKIN AGING: THE ROLE OF OXIDATIVE STRESSen_US
dc.typeArticleen_US
workflow.import.sourcescience

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Article 20.pdf
Size:
841.44 KB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
6.28 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Center for Life Sciences