RECAPPING THE FEATURES OF SARS-COV-2 AND ITS MAIN VARIANTS: STATUS AND FUTURE PATHS
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Date
2022
Authors
Ortega, Miguel A.
García-Montero, Cielo
Fraile-Martinez, Oscar
Colet, Paolo
Baizhaxynova, Ardak
Mukhtarova, Kymbat
Alvarez-Mon, Melchor
Kanatova, Kaznagul
Asúnsolo, Angel
Sarría-Santamera, Antonio
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of Personalized Medicine
Abstract
Over the two years that we have been experiencing the Severe Acute Respiratory Syndrome
Coronavirus-2 (SARS-CoV-2 ) pandemic, our challenges have been the race to develop vaccines and
the difficulties in fighting against new variants due to the rapid ability of the virus to evolve. In
this sense, different organizations have identified and classified the different variants that have been
emerging, distinguishing between variants of concern (VOC), variants of interest (VOI), or variants
under monitoring (VUM). The following review aims to describe the latest updates focusing on VOC
and already de-escalated variants, as well as to describe the impact these have had on the global
situation. Understanding the intrinsic properties of SARS-CoV-2 and its interaction with the immune
system and vaccination is essential to make out the underlying mechanisms that have led to the
appearance of these variants, helping to determine the next steps for better public management of
this pandemic.
Description
Keywords
Type of access: Open Access, SARS-CoV-2, variants, COVID-19, VOC, VOI, de-escalation, epidemiology
Citation
Ortega, M. A., García-Montero, C., Fraile-Martínez, O., Colet, P. C., Baizhaxynova, A., Mukhtarova, K., Alvarez-Mon, M., Kanatova, K., Asúnsolo, Á., & Sarría-Santamera, A. (2022). Recapping the Features of SARS-CoV-2 and Its Main Variants: Status and Future Paths. Journal of Personalized Medicine, 12(6), 995. https://doi.org/10.3390/jpm12060995