Deep phylogenetic analysis of haplogroup G1 provides estimates of SNP and STR utation rates on the human Y-Chromosome and reveals migrations of Iranic speakers

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dc.contributor.authorBalanovsky, Oleg
dc.contributor.authorZhabagin, Maxat
dc.contributor.authorAgdzhoyan, Anastasiya
dc.contributor.authorChukhryaeva, Marina
dc.contributor.authorZaporozhchenko, Valery
dc.contributor.authorUtevska, Olga
dc.contributor.authorHighnam, Gareth
dc.contributor.authorSabitov, Zhaxylyk
dc.contributor.authorGreenspan, Elliott
dc.contributor.authorDibirova, Khadizhat
dc.contributor.authorSkhalyakho, Roza
dc.contributor.authorKuznetsova, Marina
dc.contributor.authorKoshel, Sergey
dc.contributor.authorYusupov, Yuldash
dc.contributor.authorNymadawa, Pagbajabyn
dc.contributor.authorZhumadilov, Zhaxybay
dc.contributor.authorPocheshkhova, Elvira
dc.contributor.authorHaber, Marc
dc.contributor.authorZalloua, Pierre A.
dc.contributor.authorYepiskoposyan, Levon
dc.contributor.authorDybo, Anna
dc.contributor.authorTyler-Smith, Chris
dc.contributor.authorBalanovska, Elena
dc.date.accessioned2016-02-17T11:05:41Z
dc.date.available2016-02-17T11:05:41Z
dc.date.issued2015-04-07
dc.description.abstractY-chromosomal haplogroup G1 is a minor component of the overall gene pool of South- West and Central Asia but reaches up to 80% frequency in some populations scattered within this area. We have genotyped the G1-defining marker M285 in 27 Eurasian populations (n= 5,346), analyzed 367 M285-positive samples using 17 Y-STRs, and sequenced ~11 Mb of the Y-chromosome in 20 of these samples to an average coverage of 67X. This allowed detailed phylogenetic reconstruction. We identified five branches, all with high geographical specificity: G1-L1323 in Kazakhs, the closely related G1-GG1 in Mongols, G1- GG265 in Armenians and its distant brother clade G1-GG162 in Bashkirs, and G1-GG362 in West Indians.ru_RU
dc.identifier.citationBalanovsky O, Zhabagin M, Agdzhoyan A, Chukhryaeva M, Zaporozhchenko V, Utevska O, et al. (2015) Deep Phylogenetic Analysis of Haplogroup G1 Provides Estimates of SNP and STR Mutation Rates on the Human Y-Chromosome and Reveals Migrations of Iranic Speakers. PLoS ONE 10(4): e0122968. doi:10.1371/journal.pone.0122968ru_RU
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/1252
dc.language.isoenru_RU
dc.publisherPLOS ONEru_RU
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectY-chromosomal haplogroupru_RU
dc.subjecthaplogroup G1ru_RU
dc.subjectSNP and STR Mutation Ratesru_RU
dc.titleDeep phylogenetic analysis of haplogroup G1 provides estimates of SNP and STR utation rates on the human Y-Chromosome and reveals migrations of Iranic speakersru_RU
dc.typeArticleru_RU

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