The effect of intraumbilical fetal nutrition via a subcutaneously implanted port system on amino acid concentration by severe IUGR human fetuses

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Date

2017

Authors

Tchirikov, Michael
Zhumadilov, Zhaxybay
Bapayeva, Gauri
Bergner, Michael
Entezami, Michael

Journal Title

Journal ISSN

Volume Title

Publisher

J Perinat Med.

Abstract

Objective: To determine if intrauterine intraumbilical supplementation with amino acids (AA) and glucose can improve neonatal outcome of severe growth restricted human fetuses (IUGR). Methods: Prospective pilot study of intrauterine treatment of severe IUGR fetuses [n = 14, 27 weeks of gestation (range 23–31)] with erebroplacental ratio < 1, with longterm intraumbilical AA and glucose supplementation (10% of feto-placental blood volume/day) using a perinatal port system alone (n = 5) or combined with hyperbaric oxygenation (n = 1, HBO) vs. control group (n = 8).

Description

Keywords

Amino acids; cordocentesis; fetal growth restriction; HBO; hyperbaric oxygenation; intraumbilical infusion; intrauterine treatment; IUGR; port.

Citation

Tchirikov, Michael, Zhumadilov, Zhaxybay, Bapayeva, Gauri, Bergner, Michael, Entezami, Michael. (2017) The effect of intraumbilical fetal nutrition via a subcutaneously implanted port system on amino acid concentration by severe IUGR human fetuses. J Perinat Med. 45(2). 227–236 pages

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