Development of non-integrative autonomously replicating vectors for epigenetic reprogramming of somatic cells

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dc.contributor.authorShustov, A. V.
dc.contributor.authorBaltabekova, A.Zh.
dc.contributor.authorEvtyhova, L.B.
dc.contributor.authorRamankulov, Ye.M.
dc.date.accessioned2015-10-28T11:07:05Z
dc.date.available2015-10-28T11:07:05Z
dc.date.issued2013
dc.description.abstractThe idea of the project is to utilize the genome of well-described alphavirus VEE as vector for delivery and expression of the human pluripotency factors used for epigenetic reprogramming of somatic cells, namely Nanog, Oct3/4, Sox2, Klf4, and c-Myc. To date, no non-integrative viral vectors for epigenetic reprogramming of cells are available, except for the system utilizing the genome of negative strand RNA-virus, Sendai paramyxovirus.ru_RU
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/569
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectfirst research weekru_RU
dc.subjectcellsru_RU
dc.subjectinduced pluripotent stem cellsru_RU
dc.subjectvirusesru_RU
dc.titleDevelopment of non-integrative autonomously replicating vectors for epigenetic reprogramming of somatic cellsru_RU
dc.typeAbstractru_RU

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