Isolation of primary human hepatocytes from cirrhotic liver
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Date
2014
Authors
Ualiyeva, S.
Umbayev, B.
Donbay, A.
Askarova, Sholpan
Journal Title
Journal ISSN
Volume Title
Publisher
Nazarbayev University
Abstract
Chronic degenerative liver diseases are among most complex social, clinical and
epidemiological health problems worldwide. This is due to the steady increase in the incidence and
mortality of patients with this pathology. Orthotopic liver transplantation is the only way to save the
lives of patients with decompensated diffuse and focal lesions of the liver. One-year survival after liver
transplantation reaches 60-80%, but more than half of the patients on the waiting list do not survive until
operation. In this regard, hepatocyte transplantation could be an option for the patients who are on the
waiting list for organ transplantation.
Description
Keywords
chronic degenerative liver, epidemiological health, pathology, orthotopic liver, liver, hepatocyte, cirrhosis