POTENTIAL APPLICABILITY OF POLYETHYLENEIMINE PEI-COATED EU2O3 AND DY2O3 NANOPARTICLES FOR CONTRAST ENHANCEMENT IN COMPUTED TOMOGRAPHY
dc.contributor.author | Olifirenko, Valentina | |
dc.contributor.author | Abduraimova, Aiganym | |
dc.contributor.author | Kang, Moon Sung | |
dc.contributor.author | Raja, Iruthayapandi Selestin | |
dc.contributor.author | Duisenbayeva, Bakyt | |
dc.contributor.author | Molkenova, Anara | |
dc.contributor.author | Khamkhash, Laura | |
dc.contributor.author | Hwang, Yoon-Hwae | |
dc.contributor.author | Han, Dong-Wook | |
dc.contributor.author | Atabaev, Timur Sh | |
dc.date.accessioned | 2022-01-20T10:43:05Z | |
dc.date.available | 2022-01-20T10:43:05Z | |
dc.date.issued | 2021-02-15 | |
dc.description.abstract | Rare-earth metal oxide nanoparticles considered promising contrast agents for x-ray computed tomography (CT) and magnetic resonance imaging (MRI). The main purpose of this study is to investigate the potential applicability of polyethyleneimine (PEI)-coated Eu2O3 and Dy2O3 nanoparticles(NPs) for CT x-ray attenuation. Morphology and other physicochemical properties of prepared samples were systematically investigated using a range of characterization tools. Preliminary cytotoxicity experiments with L-929 fibroblastic cells suggested that both samples have no significant toxicity at concentrations below 100 μg ml−1 . Clinical CT analysis shows that PEI@Eu2O3 NPs exhibit higher x-ray attenuation efficiency (∼8 HU mM−1 ) as compared to PEI@Dy2O3 NPs(∼5 HU mM−1 ). | en_US |
dc.identifier.citation | Olifirenko, V., Abduraimova, A., Kang, M. S., Raja, I. S., Duisenbayeva, B., Molkenova, A., Khamkhash, L., Hwang, Y. H., Han, D. W., & Atabaev, T. S. (2021). Potential applicability of polyethyleneimine PEI-coated Eu2O3 and Dy2O3 nanoparticles for contrast enhancement in computed tomography. Nano Express, 2(1), 010022. https://doi.org/10.1088/2632-959x/abe343 | en_US |
dc.identifier.uri | http://nur.nu.edu.kz/handle/123456789/5985 | |
dc.language.iso | en | en_US |
dc.publisher | Nano Express | en_US |
dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
dc.subject | Type of access: Open Access | en_US |
dc.subject | Eu2O3, Dy2O3 | en_US |
dc.subject | nanoparticles | en_US |
dc.subject | CT contrast agents | en_US |
dc.subject | cytotoxicity | en_US |
dc.subject | polyethyleneimine | en_US |
dc.title | POTENTIAL APPLICABILITY OF POLYETHYLENEIMINE PEI-COATED EU2O3 AND DY2O3 NANOPARTICLES FOR CONTRAST ENHANCEMENT IN COMPUTED TOMOGRAPHY | en_US |
dc.type | Article | en_US |
workflow.import.source | science |