POTENTIAL APPLICABILITY OF POLYETHYLENEIMINE PEI-COATED EU2O3 AND DY2O3 NANOPARTICLES FOR CONTRAST ENHANCEMENT IN COMPUTED TOMOGRAPHY

dc.contributor.authorOlifirenko, Valentina
dc.contributor.authorAbduraimova, Aiganym
dc.contributor.authorKang, Moon Sung
dc.contributor.authorRaja, Iruthayapandi Selestin
dc.contributor.authorDuisenbayeva, Bakyt
dc.contributor.authorMolkenova, Anara
dc.contributor.authorKhamkhash, Laura
dc.contributor.authorHwang, Yoon-Hwae
dc.contributor.authorHan, Dong-Wook
dc.contributor.authorAtabaev, Timur Sh
dc.date.accessioned2022-01-20T10:43:05Z
dc.date.available2022-01-20T10:43:05Z
dc.date.issued2021-02-15
dc.description.abstractRare-earth metal oxide nanoparticles considered promising contrast agents for x-ray computed tomography (CT) and magnetic resonance imaging (MRI). The main purpose of this study is to investigate the potential applicability of polyethyleneimine (PEI)-coated Eu2O3 and Dy2O3 nanoparticles(NPs) for CT x-ray attenuation. Morphology and other physicochemical properties of prepared samples were systematically investigated using a range of characterization tools. Preliminary cytotoxicity experiments with L-929 fibroblastic cells suggested that both samples have no significant toxicity at concentrations below 100 μg ml−1 . Clinical CT analysis shows that PEI@Eu2O3 NPs exhibit higher x-ray attenuation efficiency (∼8 HU mM−1 ) as compared to PEI@Dy2O3 NPs(∼5 HU mM−1 ).en_US
dc.identifier.citationOlifirenko, V., Abduraimova, A., Kang, M. S., Raja, I. S., Duisenbayeva, B., Molkenova, A., Khamkhash, L., Hwang, Y. H., Han, D. W., & Atabaev, T. S. (2021). Potential applicability of polyethyleneimine PEI-coated Eu2O3 and Dy2O3 nanoparticles for contrast enhancement in computed tomography. Nano Express, 2(1), 010022. https://doi.org/10.1088/2632-959x/abe343en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/5985
dc.language.isoenen_US
dc.publisherNano Expressen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectType of access: Open Accessen_US
dc.subjectEu2O3, Dy2O3en_US
dc.subjectnanoparticlesen_US
dc.subjectCT contrast agentsen_US
dc.subjectcytotoxicityen_US
dc.subjectpolyethyleneimineen_US
dc.titlePOTENTIAL APPLICABILITY OF POLYETHYLENEIMINE PEI-COATED EU2O3 AND DY2O3 NANOPARTICLES FOR CONTRAST ENHANCEMENT IN COMPUTED TOMOGRAPHYen_US
dc.typeArticleen_US
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