HONEY COMBINATION THERAPIES FOR SKIN AND WOUND INFECTIONS: A SYSTEMATIC REVIEW OF THE LITERATURE

Simple item page
dc.contributor.authorMcLoone, Pauline
dc.contributor.authorTabys, Dina
dc.contributor.authorFyfe, Lorna
dc.date.accessioned2021-07-14T07:49:46Z
dc.date.available2021-07-14T07:49:46Z
dc.date.issued2020-11-24
dc.description.abstractTopical application of medical grade honey is recommended for the clinical management of wound infections. The suitability of honey as a wound healing agent is largely due to its antibacterial activity, immune modulatory properties, and biocompatibility. Despite the usefulness of honey in wound healing, chronic wound infections continue to be a global problem requiring new and improved therapeutic interventions. Several recent studies have investigated the effects of combining honey with other therapies or agents with the aim of finding more efficacious treatments. In this systematic review, the database PubMed was used to carry out a search of the scientific literature on the combined effects of honey and other therapies on antimicrobial activity and wound and skin healing. The search revealed that synergistic or additive antimicrobial effects were observed in vitro when honey was combined with antibiotics, bacteriophages, antimicrobial peptides, natural agents, eg, ginger or propolis and other treatment approaches such as the use of chitosan hydrogel. Outcomes depended on the type of honey, the combining agent or treatment and the microbial species or strain. Improved wound healing was also observed in vivo in mice when honey was combined with laser therapy or bacteriophage therapy. More clinical studies in humans are required to fully understand the effectiveness of honey combination therapies for the treatment of skin and wound infections.en_US
dc.identifier.citationHoney Combination Therapies for Skin and Wound Infections: A Systematic Review of the Literature. Clinical, Cosmetic and Investigational Dermatology, Volume 13, 875–888. https://doi.org/10.2147/ccid.s282143en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/5568
dc.language.isoenen_US
dc.publisherClinical, Cosmetic and Investigational Dermatologyen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjecthoneyen_US
dc.subjectType of access: Open Accessen_US
dc.subjectantibioticsen_US
dc.subjectnatural agentsen_US
dc.subjectcombination therapyen_US
dc.subjectwound infectionen_US
dc.subjectskin infectionen_US
dc.titleHONEY COMBINATION THERAPIES FOR SKIN AND WOUND INFECTIONS: A SYSTEMATIC REVIEW OF THE LITERATUREen_US
dc.typeArticleen_US
workflow.import.sourcescience

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ccid-282143-honey-combination-therapies-for-skin-and-wound-infections-a.pdf
Size:
993 KB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
6.28 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Articles