Z-DNA forming regions in the human genome

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Date

2014

Authors

Fujimoto, Y.
Schonbach, C.

Journal Title

Journal ISSN

Volume Title

Publisher

Nazarbayev University

Abstract

Z-DNA is the left-handed helical structure of the usually right-handed B-DNA double helix structure. Z-DNA conformations have been found to cause mutagenesis and genetic instability [1]. In this study, human genome sequences potentially forming Z-DNA regions (ZDRs) were extracted and analysed for functional implications.

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Keywords

Z-DNA, human genome, gene ontology, chromosomes

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