Pediatric Celiac Disease in Central and East Asia: Current Knowledge and Prevalence

dc.contributor.authorPoddighe, Dimitri
dc.contributor.authorRakhimzhanova, Marzhan
dc.contributor.authorMarchenko, Yelena
dc.contributor.authorCatassi, Carlo
dc.date.accessioned2019-04-25T06:51:06Z
dc.date.available2019-04-25T06:51:06Z
dc.date.issued2019-01-12
dc.description.abstractThe current prevalence of pediatric Celiac Disease (CD) is estimated to be around 1% in the general population, worldwide. However, according to the geographic area, a great variability of CD prevalence has been described. Whereas a number of studies are available from Europe, North and South America, Australia, South-West Asia, and North Africa, the knowledge and awareness of CD in large parts of the remaining world areas is definitively poor. In several countries of Central and East Asia, the consumption of wheat is consistent and/or has significantly increased in recent decades, and CD is supposed to be underdiagnosed in children. In this mini-review, we aimed to summarize the current knowledge about the prevalence of pediatric CD in Central and East Asia, paying attention to the HLA-DQ immunogenetic background as well. Indeed, CD is likely not to be as uncommon as previously or currently thought in countries like Russia, Kazakhstan, and China, in addition to India, where pediatric CD has been clearly showed to be quite prevalent. Therefore, there is an urgent need for population-based studies on the prevalence of CD in those countries, especially in children, in order to increase the awareness of this disease and to improve the diagnostic strategy in these areas.en_US
dc.identifier.urihttp://dx.doi.org/10.3390/medicina55010011
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/3846
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectceliac diseaseen_US
dc.subjectchildrenen_US
dc.subjectHLA-DQen_US
dc.subjectprevalenceen_US
dc.subjectAsiaen_US
dc.titlePediatric Celiac Disease in Central and East Asia: Current Knowledge and Prevalenceen_US
dc.typeArticleen_US
workflow.import.sourcescience

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