PREVALENCE OF HIGH-RISK HUMAN PAPILLOMAVIRUS INFECTION AMONG KAZAKHSTANI WOMEN WITH ABNORMAL CERVICAL CYTOLOGY

Abstract

Aim: This study aims to determine prevalence of HR-HPV in Kazakhstani women with abnormal cervical cytology results. The hypothesis is that HR-HPV prevalence will be high among these women. Methods: An anonymous patient database (de-identified patient records) will be used for data analysis. Statistical analysis will be carried out with STATA 16. Results: Women with abnormal cytology were slightly older (mean age: 36.8) than those with no abnormal cytology (mean age: 36.0). The most prevalent age group in both categories was 25-34. Overall frequency of HPV was higher among women with abnormal cytology (81.6%) compared to those with no abnormal cytology (39.5%). HPV16 was the most frequent type, observed in 28.4% of women with abnormal cytology and 9.2% of women with no abnormal cytology. Multiple HPV infections were more frequent in women with abnormal cytology, particularly co-infections of HPV16 and HPV18. Conclusion: This study highlights the high prevalence of HPV infection in Kazakhstani women with abnormal cervical cytology, with HPV 16 and HPV 18 being the most prevalent types. The findings support the need for targeted HPV vaccination and enhanced screening programs to prevent cervical cancer in Kazakhstan.