OPTIC NERVE ULTRASONOGRAPHY FOR DETECTING INTRACRANIAL PRESSURE IN PATIENTS WITH CEREBROVASCULAR DISEASES: A SYSTEMATIC REVIEW

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Date

2024-04-23

Authors

Tungushpayev, Meiram

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Publisher

Nazarbayev University School of Medicine

Abstract

Introduction: Ultrasonography shows potential as a diagnostic method for identifying intracranial hypertension. Nevertheless, its diagnostic performance in measuring optic nerve parameters remains ambiguous. To address this uncertainty and assess its significance in clinical practice, a systematic review of the literature was conducted. Methods: A systematic search was carried out across PubMed, Google Scholar, and the Cochrane Library databases. The quality of evidence was evaluated utilizing the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology, while the risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) checklist. Results: 507 records were identified, following the removal of 499 records, 8 observational studies remained for final review covering 329 participants. The reported diagnostic accuracy of ultrasonography ranged between 58.8% to 100% concerning sensitivity, 67% to 100% for specificity, 43.5% to 100% for positive predictive values (PPV), and 50% to 100% for negative predictive values (NPV). Conclusion: The literature suggests that ultrasonography demonstrates comparable accuracy to reference computed tomography in measuring the optic nerve, but depends on the expertise of the sonographer. Further investigation is required to fully understand its diagnostic performance.

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Citation

Tungushpayev, M. (2024). Optic Nerve Ultrasonography for Detecting Intracranial Pressure in Patients with Cerebrovascular Diseases: A Systematic Review. Nazarbayev University School of Medicine