A RETROSPECTIVE ANALYSIS OF PHARMACOTHERAPY IN KAZAKHSTAN: ASSESSMENT OF THE RATIONAL PRESCRIPTION AND USE OF ANTIBIOTICS IN THE NEPHROLOGY DEPARTMENT OF A MULTIDISCIPLINARY HOSPITAL
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Date
2022
Authors
Assan, Ainur
Moldaliyev, Ikilas
Kerimbayeva, Zakira
Gaipov, Abduzhappar
Utepova, Dinara
Magzumova, Raushangul Z
Tsoy, Lyudmila
Issayev, Ali
Aljofan, Mohamad
Journal Title
Journal ISSN
Volume Title
Publisher
Electronic Journal of General Medicine
Abstract
Introduction: The rapid development of the pharmaceutical industry has increased the need to assess and
monitor the use of medicines. Thus, necessitates the importance of monitoring the appropriate use of medicines
including antimicrobials.
Objective: Pharmacoeconomic analysis of pharmacotherapy in the nephrology department at a multidisciplinary
hospital.
Methods: The study is a retrospective analysis of medicine use and expenditure. The study utilized the ABC-VEN
analysis of medical use and the WHO-AWaRe-2021 analysis of antibiotic use, to determine the prescription and
financial trends of the nephrology department (30 beds) of a multidisciplinary regional hospital (total 844 beds) in
Turkestan, Kazakhstan 2018-2021.
Results: The analyzedcosts of drugs included 116 international nonproprietary names prescribed to patients from
the nephrology department during the study period. In total, pharmacotherapy costs increased by 52.6% in 2021
compared to 2018. Five INN drugs were purchased without their inclusion in the Kazakhstan National Medicinal
Formulary, such as atropine sulfate, sodium bicarbonate, sodium chloride (crystalline salt), nitroxoline, and
nitrofural. The pharmacoeconomics analysis of antibiotics usage for 2018-2021 showed a sharp increase in
the%age of costs.
Conclusion: The study showed an increase in funding for pharmacotherapy in the department of nephrology,
which increases the availability of medicines. However, the trend in prescribing drugs with poor evidence base
level, and the increase in the proportion of antibiotic prescription, require immediate intervention including the
utilization of clinical pharmacy services for regular assessment of the pharmacoeconomic feasibility of antibiotic
therapy. This will improve the quality of medical care and reduce the financial costs.
Description
Keywords
Type of access: Open Access, nephrology, ABC/VEN, AWaRe, drug efficacy, safety
Citation
Assan, A., Moldaliyev, I., Kerimbayeva, Z., Gaipov, A., Utepova, D., Magzumova, R. Z., Tsoy, L., Issayev, A., & Aljofan, M. (2022). A retrospective analysis of pharmacotherapy in Kazakhstan: Assessment of the rational prescription and use of antibiotics in the nephrology department of a multidisciplinary hospital. Electronic Journal of General Medicine, 19(6), em422. https://doi.org/10.29333/ejgm/12576