Childhood cancers: what is a possible role of infectious agents?
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Date
2013
Authors
Alibek, Kenneth
Mussabekova, Assel
Kakpenova, Ainur
Duisembekova, Assem
Baiken, Yeldar
Aituov, Bauyrzhan
Karatayeva, Nargis
Zhussupbekova, Ainur
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Publisher
BMC
Abstract
The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed.
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Keywords
Research Subject Categories::MEDICINE, cancer, Childhood cancers, CC, Central nervous system, CNS, lymphoblastic lymphoma, LL, BL, Burkitt’s lymphoma
Citation
Alibek, K., Mussabekova, A., Kakpenova, A., Duisembekova, A., Baiken, Y., Aituov, B., Karatayeva, N., & Zhussupbekova, S. (2013). Childhood cancers: what is a possible role of infectious agents? Infectious Agents and Cancer, 8(1), 48. https://doi.org/10.1186/1750-9378-8-48
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Except where otherwised noted, this item's license is described as Attribution-NonCommercial-ShareAlike 3.0 United States