CARBON DOTS-MEDIATED FLUORESCENT SCAFFOLDS: RECENT TRENDS IN IMAGE-GUIDED TISSUE ENGINEERING APPLICATIONS
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Date
2021-05-20
Authors
Vedhanayagam, Mohan
Raja, Iruthayapandi Selestin
Molkenova, Anara
Atabaev, Timur Sh.
Sreeram, Kalarical Janardhanan
Han, Dong-Wook
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI AG
Abstract
Regeneration of damaged tissues or organs is one of the significant challenges in tissue engineering and regenerative medicine. Many researchers have fabricated various scaffolds to accelerate the tissue regeneration process. However, most of the scaffolds are limited in clinical trials due to scaffold inconsistency, non-biodegradability, and lack of non-invasive techniques to monitor tissue regeneration after implantation. Recently, carbon dots (CDs) mediated fluorescent scaffolds are widely explored for the application of image-guided tissue engineering due to their controlled architecture, light-emitting ability, higher chemical and photostability, excellent biocompatibility, and biodegradability. In this review, we provide an overview of the recent advancement of CDs in terms of their different synthesis methods, tunable physicochemical, mechanical, and optical properties, and their application in tissue engineering. Finally, this review concludes the further research directions that can be explored to apply CDs in tissue engineering.
Description
Keywords
Biodegradation, Carbon dots, Fluorescent scaffold, Image-guided tissue engineering, Mechanical strength, Type of access: Open Access
Citation
Vedhanayagam, M., Raja, I. S., Molkenova, A., Atabaev, T. Sh., Sreeram, K. J., & Han, D.-W. (2021). Carbon Dots-Mediated Fluorescent Scaffolds: Recent Trends in Image-Guided Tissue Engineering Applications. International Journal of Molecular Sciences, 22(10), 5378. https://doi.org/10.3390/ijms22105378