Assessment of Risk Factors of Helicobacter Pylori Infection and Peptic Ulcer Disease
| dc.contributor.author | Mhaskar, Rahul S. | |
| dc.contributor.author | Ricardo, Izurieta | |
| dc.contributor.author | Azizan, Azliyati | |
| dc.contributor.author | Laxminarayan, Rajaram | |
| dc.contributor.author | Amol, Bapaye | |
| dc.contributor.author | Santosh, Walujkar | |
| dc.contributor.author | Boo, Kwa | |
| dc.date.accessioned | 2015-12-30T05:19:21Z | |
| dc.date.available | 2015-12-30T05:19:21Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | Background: Helicobacter pylori (H. pylori) infection is a risk factor for peptic ulcer. There have been no studies addressing environmental and dietary risk factors in western India. We conducted a case control study enrolling peptic ulcer patients in Pune, India. Materials and Methods: Risk factors for peptic ulcer and H. pylori infection were assessed in a participant interview. H. pylori status was assessed from stool by monoclonal antigen detection. Results: We enrolled 190 peptic ulcer, 35 stomach cancer patients, and 125 controls. Fifty-one percent (180/350) of the participants were infected with H. pylori. Lower socioeconomic status (SES) [odds ratio (OR): 1.10, 95% confidence interval (CI): 1.02-1.39], meat consumption (OR: 2.35, 95% CI: 1.30-4.23), smoking (OR: 2.23, 95% CI: 1.24-4.02), eating restaurant food (OR: 3.77, 95% CI: 1.39-10.23), and drinking nonfiltered or nonboiled water (OR: 1.05, 95% CI: 1.01-1.23) were risk factors for H. pylori infection. H. pylori infection (OR: 1.70, 95% CI:I. 03-2.89), meat (OR: 1.10, 95% CI: 1.02-1.75), fish (OR: 1.05, 95% CI: 1.02-1.89) consumption, and a family history of ulcer (OR: 1.20, 95% CI: 1.08-1.60) were risk factors for peptic ulcer. Consumption of chili peppers (OR: 0.20, 95% CI: 0.10-0.37) and parasite infestation (OR: 0.44, 95% CI: 0.24-0.80) were protective against H. pylori infection. Conclusion: H. pylori infection is associated with peptic ulcer. Lower SES, consumption of restaurant food, meat, nonfiltered water, and smoking are risk factors for H. pylori. Consumption of meat, fish, and a family history of peptic ulcer are risk factors for peptic ulcer. Consumption of chili peppers and concurrent parasite infestation appear to be protective against H. pylori. | ru_RU |
| dc.identifier.uri | http://nur.nu.edu.kz/handle/123456789/985 | |
| dc.language.iso | en | ru_RU |
| dc.publisher | Journal of Global Infectious Diseases | ru_RU |
| dc.subject | Case control study | ru_RU |
| dc.subject | Chili peppers | ru_RU |
| dc.subject | Helicobacter pylori | ru_RU |
| dc.subject | India | ru_RU |
| dc.subject | Parasites | ru_RU |
| dc.subject | Pune | ru_RU |
| dc.title | Assessment of Risk Factors of Helicobacter Pylori Infection and Peptic Ulcer Disease | ru_RU |
| dc.type | Article | ru_RU |