Glial cells and their molecules in nerve regeneration

Abstract

Peripheral nerve injury has many causes ranging from traumatic damage to metabolic disturbances (e.g.in diabetes mellitus). The primary pathology can affect axons (nerve transection) or Schwann cells, and their interdependence means that injury to one will ultimately affect the other. Fortunately, the PNS has a significant capacity for repair, and axons are able to regenerate over long distances and are also capable of remyelination.