Screening mutation in RYR2 gene in a Kazakhstani idiopathic ventricular tachycardia study cohort: two novel mutations
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Date
2014
Authors
Akilzhanova, A.
Guelly, C.
Abilova, Z. M.
Rakhimova, S.
Nuralinov, O. M.
Abdrakhmanov, A. C.
Bekbosynova, M. S.
Journal Title
Journal ISSN
Volume Title
Publisher
Nazarbayev University
Abstract
The human ryanodine receptor 2 (RYR2) is one of the key players tightly regulating
calcium efflux from the sarcoplasmic reticulum to the cytosol and found frequently mutated (<60%) in
context of catecholaminergic polymorphic ventricular tachycardia (CPVT1) [1].
Description
Keywords
ventricular tachycardia, ventricular arrhythmia, RYR2 gene