Nuclear abnormalities in aspirated thyroid cells and chromosome aberrations in lymphocytes of residents near the Semipalatinsk Nuclear Test Site
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Date
2006
Authors
Takeichi, Nobuo
Hoshi, Masaharu
Iida, Shozo
Tanaka, Kimio
Harada, Yuka
Zhumadilov, Zhaxybay
Chaizhunusova, Nailya
Apsalikov, Kazbek N.
Noso, Yoshihiro
Inaba, Toshiya
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of Radiation Research. http://jrr.jstage.jst.go.jp
Abstract
Chromosomal studies in peripheral lymphocytes from 63 residents near the Semipalatinsk nuclear test site, at ages of 52–63 years old, were performed in 2001–2002. A higher rate of chromosome aberrations was observed in the two contaminated villages, Dolon and Sarjal, compared with the control village,
Kokpekti. Moreover, a relationship of frequency of cells with radiation induced chromosome aberrations and the previously estimated exposure dose was observed. Furthermore, apparent nuclear abnormalities (ANA) of thyroid follicular cells were studied in 30 out of 63 residents, who were examined for chromosome aberrations. A higher rate of ANA was also found in the residents in the exposed villages compared with those in the control village. These results suggest radiation effects both on the chromosomes in
peripheral lymphocytes and on the follicular cells in the thyroid.
Description
Keywords
Semipalatinsk nuclear test site, thyroid cells, apparent nuclear abnormalities, chromosome aberrations, radiation effect