3D PRINTING OF BIOCOMPATIBLE CRYOGELS FOR BONE TISSUE ENGINEERING

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dc.contributor.authorMoazzam, Muhammad
dc.date.accessioned2023-06-13T08:42:43Z
dc.date.available2023-06-13T08:42:43Z
dc.date.issued2023
dc.description.abstractNatural biopolymers are highly valued and commonly utilized in tissue engineering to create scaffolds that support living cells. This is due to their exceptional biocompatibility and the fact that their degradation rate can be controlled. However, the shape and average pore size are crucial in biological processes that influence the kinetics of cell proliferation and tissue regeneration processes linked to the production of extracellular matrix. For the construction of high-accuracy hydrogel scaffolds via 3D printing, the shear thinning characteristics of the bioinks used frequently result in morphological compromises like smaller pore diameters. Here, we introduced a new mixture of gelatin and oxidized alginate (Gel/OxAlg) that has been optimized for use in 3D printing and cryogelation techniques. This composite formulation allows for the creation of highly porous and biocompatible hydrogel scaffolds with extra-large pore sizes (d > 100 μm) using a combination of 3D printing and cryogelation techniques. These scaffolds have the potential to serve as a platform for various tissue engineering applications, and their morphological properties and cell viability data can be tailored accordingly. Overall, our approach offers a simple and cost-effective method for constructing hydrogel scaffolds with high accuracy.en_US
dc.identifier.citationMoazzam, M. (2023). 3d printing of biocompatible cryogels for bone tissue engineering. School of Engineering and Digital Sciencesen_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/7217
dc.language.isoenen_US
dc.publisherSchool of Engineering and Digital Sciencesen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectType of access: Open Accessen_US
dc.subject3d printingen_US
dc.subjectbiocompatible cryogelsen_US
dc.subjectbone tissue engineeringen_US
dc.title3D PRINTING OF BIOCOMPATIBLE CRYOGELS FOR BONE TISSUE ENGINEERINGen_US
dc.typeMaster's thesisen_US
workflow.import.sourcescience

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