REVIEW OF COVID-19 TESTING AND DIAGNOSTIC METHODS

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dc.contributor.authorFilchakova, Olena
dc.contributor.authorDossym, Dina
dc.contributor.authorIlyas, Aisha
dc.contributor.authorKuanysheva, Tamila
dc.contributor.authorAbdizhamil, Altynay
dc.contributor.authorBukasov, Rostislav
dc.date.accessioned2022-07-20T04:40:17Z
dc.date.available2022-07-20T04:40:17Z
dc.date.issued2022
dc.description.abstractMore than six billion tests for COVID-19 has been already performed in the world. The testing for SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and corresponding human antibodies is essential not only for diagnostics and treatment of the infection by medical institutions, but also as a pre-requisite for major semi-normal economic and social activities such as international flights, off line work and study in offices, access to malls, sport and social events. Accuracy, sensitivity, specificity, time to results and cost per test are essential parameters of those tests and even minimal improvement in any of them may have noticeable impact on life in the many countries of the world. We described, analyzed and compared methods of COVID-19 detection, while representing their parameters in 22 tables. Also, we compared test performance of some FDA approved test kits with clinical performance of some non-FDA approved methods just described in scientific literature. RT-PCR still remains a golden standard in detection of the virus, but a pressing need for alternative less expensive, more rapid, point of care methods is evident. Those methods that may eventually get developed to satisfy this need are explained, discussed, quantitatively compared. The review has a bioanalytical chemistry prospective, but it may be interesting for a broader circle of readers who are interested in understanding and improvement of COVID-19 testing, helping eventually to leave COVID-19 pandemic in the past.en_US
dc.identifier.citationFilchakova, O., Dossym, D., Ilyas, A., Kuanysheva, T., Abdizhamil, A., & Bukasov, R. (2022). Review of COVID-19 testing and diagnostic methods. Talanta, 244, 123409. https://doi.org/10.1016/j.talanta.2022.123409en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/6469
dc.language.isoenen_US
dc.publisherTalantaen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectType of access: Open Accessen_US
dc.subjectCOVID-19 testsen_US
dc.subjectSARS CoV-2en_US
dc.subjectAntibody to SARS-CoV-2en_US
dc.subjectRT-PCR of SARS CoV-2en_US
dc.subjectCRISPRen_US
dc.subjectLAMPen_US
dc.subjectELISAen_US
dc.subjectCLIAen_US
dc.subjectLateral flow immunoassaysen_US
dc.subjectRapid detectionen_US
dc.subjectCT scanningen_US
dc.subjectUltrasound scanningen_US
dc.subjectTime to resultsen_US
dc.subjectFalse positive resultsen_US
dc.subjectFalse negative resultsen_US
dc.titleREVIEW OF COVID-19 TESTING AND DIAGNOSTIC METHODSen_US
dc.typeArticleen_US
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