RETROSPECTIVE ANALYSIS OF THE RELATIONSHIP BETWEEN TWO ANTHRAX OUTBREAKS IN KAZAKHSTAN BASED ON GENOMIC DATA

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Date

2020-12-10

Authors

Shevtsov, Alexandr
Vergnaud, Gilles
Amirgazin, Asylulan
Lukhnova, Larissa
Izbanova, Uinkul
Shevtsov, Vladislav

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Microbiology

Abstract

We present a retrospective analysis of strains from two anthrax outbreaks in western Kazakhstan in 2009. The outbreaks occurred during the same period and in the same area located close to main roads, favoring a single source of infection. However, multilocus variable-number tandem-repeat analysis (MLVA), canonical single-nucleotide polymorphism (CanSNP) analysis, and genome-wide analysis demonstrated that the outbreaks were not connected.

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Keywords

canonical single-nucleotide polymorphism, CanSNP, MLVA, multilocus variable-number tandem-repeat analysis, Research Subject Categories::NATURAL SCIENCES, anthrax outbreaks, genomic data

Citation

Alexandr Shevtsov, Gilles Vergnaud, Asylulan Amirgazin, Larissa Lukhnova, Uinkul Izbanova, Vladislav Shevtsov, Yerlan Ramankulov Microbiology Resource Announcements Dec 2020, 9 (50) e01126-20; DOI: 10.1128/MRA.01126-20

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