APPLICATION OF NANOMATERIALS IN MICROWAVE AND RADIOFREQUENCY ABLATION CANCER THERAPY

Abstract

Cancer is one of the leading causes of death worldwide. Treating cancer has become of great interest. Different approaches have been suggested in this purpose. Current techniques usually employ massive apparatus or resection. Thermal ablation is known as a promising technique which allows to treat tumors in minimally invasive way. In contrast to standard treatment, thermal therapy is associated with smaller equipment. Thermal therapy executes different energy sources as radiofrequency (RF), microwave (MW), laser, or photothermal ablation. Nanomaterials are known to enhance effect of this therapy. Current methods employ different coatings and combinations of nanomaterials. This research investigates effect of concentration and size of nanoparticles on RFA and MWA, respectively. It was found that presence of AuNPs contribute to increase of ablation area and more uniform heating in RFA.