Rapid detection of vaccinia virus using biofunctionalized fiber-optic ball-tip biosensors

Simple item page
dc.contributor.authorAida Rakhimbekova
dc.contributor.authorBaizak Kudaibergenov
dc.contributor.authorKuanysh Seitkamal
dc.contributor.authorAurora Bellone
dc.contributor.authorAyazhan Dauletova
dc.contributor.authorMarzhan Sypabekova
dc.contributor.authorMassimo Olivero
dc.contributor.authorGuido Perrone
dc.contributor.authorAntonia Radaelli
dc.contributor.authorCarlo Zanotto
dc.contributor.authorCarlo De Giuli Morghen
dc.contributor.authorLuca Vangelista
dc.contributor.authorDaniele Tosi
dc.date.accessioned2025-08-22T10:15:34Z
dc.date.available2025-08-22T10:15:34Z
dc.date.issued2023-10-14
dc.description.abstractIn this work, we present the development and biofunctionalization of a fiber-optic ball-resonator biosensor for the real-time detection of vaccinia poxvirus. We fabricated several ball-tip resonators, functionalized through a silanization process to immobilize two bioreceptors: the monoclonal anti-L1R antibody targeting the L1R protein, and the polyclonal rabbit serum antibodies targeting the whole vaccinia virus (VV) pathogen. Experimental measurements were carried out to detect VV in concentrations from 10en
dc.identifier.citationRakhimbekova Aida, Kudaibergenov Baizak, Seitkamal Kuanysh, Bellone Aurora, Dauletova Ayazhan, Sypabekova Marzhan, Olivero Massimo, Perrone Guido, Radaelli Antonia, Zanotto Carlo, De Giuli Morghen Carlo, Vangelista Luca, Tosi Daniele. (2023). Rapid detection of vaccinia virus using biofunctionalized fiber-optic ball-tip biosensors. Scientific Reports. https://doi.org/https://doi.org/10.1038/s41598-023-44926-6en
dc.identifier.doi10.1038/s41598-023-44926-6
dc.identifier.urihttps://doi.org/10.1038/s41598-023-44926-6
dc.identifier.urihttps://nur.nu.edu.kz/handle/123456789/9901
dc.language.isoen
dc.publisherSpringer Science and Business Media LLC
dc.relation.ispartofScientific Reportsen
dc.rightsAll rights reserveden
dc.sourceScientific Reports, (2023)en
dc.subjectVacciniaen
dc.subjectPolyclonal antibodiesen
dc.subjectDetection limiten
dc.subjectBiosensoren
dc.subjectHerpes simplex virusen
dc.subjectMonoclonal antibodyen
dc.subjectVirusen
dc.subjectMaterials scienceen
dc.subjectVirologyen
dc.subjectAntibodyen
dc.subjectChemistryen
dc.subjectBiologyen
dc.subjectNanotechnologyen
dc.subjectChromatographyen
dc.subjectRecombinant DNAen
dc.subjectImmunologyen
dc.subjectGeneen
dc.subjectBiochemistryen
dc.subjecttype of access: open accessen
dc.titleRapid detection of vaccinia virus using biofunctionalized fiber-optic ball-tip biosensorsen
dc.typearticleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Rapid_detection_of_vaccinia_virus_using_biofunctionalized_fiber-optic_ball-tip_biosensors__4b9121db.pdf
Size:
2.92 MB
Format:
Adobe Portable Document Format
Download

Collections

Articles