Type 1 Diabetes: Current Perspectives

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dc.contributor.authorKozhakhmetova, A
dc.contributor.authorGillespie, KM
dc.date.accessioned2019-09-09T09:45:46Z
dc.date.available2019-09-09T09:45:46Z
dc.date.issued2016
dc.description.abstractType 1 diabetes, resulting from the autoimmune destruction of insulin producing islet beta cells is caused by genetic and environmental determinants. Recent studies agree that counterintuitively, the major genetic susceptibility factors are decreasing in frequency as the incidence of the condition increases. This suggests a growing role for environmental determinants but these have been difficult to identify and our understanding of gene/environment effects are limited. Individuals "at-risk" can be identified accurately through the presence of multiple islet autoantibodies and current efforts in type 1 diabetes research focus on improved biomarkers and strategies to prevent or reverse the condition through immunotherapy.en_US
dc.identifier.citationKozhakhmetova A(1), Gillespie KM(2). Type 1 Diabetes: Current Perspectives. Methods Mol Biol. 2016;1433:1-9. doi: 10.1007/7651_2015_289.en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/4228
dc.language.isoenen_US
dc.publisherMethods in Molecular Biologyen_US
dc.subjectAutoimmunity; Genes; Insulin; Islet autoantibodies; Type 1 diabetesen_US
dc.titleType 1 Diabetes: Current Perspectivesen_US
dc.typeBook chapteren_US
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