Evaluation of the modified HTK solution in pancreas transplantationdAn experimental model

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Date

2016

Authors

Esmaeilzadeh, Majid
Fonouni, Hamidreza
Golriz, Mohammad
Majlesara, Ali
Kuttymuratov, Gani
Bergmann, Frank
Jarahian, Parvin
Khazaeipour, Zahra
Faridar, Alireza
Tahmasbi, Morva

Journal Title

Journal ISSN

Volume Title

Publisher

Asian Journal of Surgery

Abstract

One of the great challenges in pancreas transplantation is the ischemia reperfusion injury. It is mentioned that free oxygen and/or nitrogen radicals play a prominent role in this phase. To minimize this problem, a modified histidineetryptophan eketoglutarate (HTK) solution that contains modified antioxidants has been developed. Our aim was to evaluate this solution in improving the viability of the pancreas in comparison with standard HTK and University of Wisconsin (UW) solutions in a porcine model of pancreas transplantation.

Description

Keywords

histidine tryptophan ketoglutarate, ischemia reperfusion injury, pancreas transplantation, University of Wisconsin

Citation

Majid Esmaeilzadeh, Hamidreza Fonouni, Mohammad Golriz, Ali Majlesara, Gani Kuttymuratov, Frank Bergmann, Parvin Jarahian, Zahra Khazaeipour, Alireza Faridar, Morva Tahmasbi Rad, Thomas Longerich, Martha M. Gebhard and Arianeb Mehrabi. (2016) Evaluation of the modified HTK solution in pancreas transplantationdAn experimental model. Asian Journal of Surgery. Volume 39. Issue 2. Pages 66-73

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