RETROSPECTIVE ANALYSIS OF GRAFT SURVIVAL INCIDENCE AFTER KIDNEY TRANSPLANTATION IN KAZAKHSTAN

Abstract

Nowadays, graft survival after kidney transplantation has become a heated issue. The incidence of graft loss remained high for years. This is also true for Kazakhstan, where according to the latest data (2018) the graft loss was 90% in a 10-year time period. The aim of this retrospective study is to evaluate the rate of graft survival in Kazakhstan using the latest available data and identify the factors affecting the graft loss. The significance of this study is that the results obtained show more recent epidemiological situation in Kazakhstan and update the existing data on graft survival. The materials and methods included the collection of raw data from the Unified National Electronic Health System and statistical analysis such as Cox Proportional Hazards Survival Regression test. The results obtained are the following: the rate of the graft survival is 64% while the incidence rate of graft loss is 36%. The analysis of factors that affect the graft survival showed no statistical significance due to the small sample size (77), hence not included in the final results. Overall, the study demonstrated the importance of collecting large database to evaluate the rate of graft survival after kidney transplantation.