Browsing School of Science and Technology (2015-2019) by Author "Zhubanchaliyev, Altynbek"

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Targeting Mechanotransduction at theTranscriptional Level: YAPandBRD4 Are Novel Therapeutic Targets for the Reversal of Liver Fibrosis

Zhubanchaliyev, Altynbek; Temirbekuly, Aibar; Kongrtay, Kuralay; Wanshura, Leah C.; Kunz, Jeannette (Frontiers in Pharmacology, 2016-12-01)

Liver fibrosis is the result of a deregulated wound healing process characterized by the excessive deposition of extracellular matrix. Hepatic stellate cells (HSCs), which are activated in response to liver injury, are the ...