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Browsing School of Science and Technology (2015-2019) by Subject "Research Subject Categories::NATURAL SCIENCES::Biology"

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Browsing School of Science and Technology (2015-2019) by Subject "Research Subject Categories::NATURAL SCIENCES::Biology"

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  • Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study 
    Sikhayeva, Nurgul; Iskakova, Aisha; Saigi-Morgui, Nuria; Zholdybaeva, Elena; Eap, Chin-Bin; Ramanculov, Erlan (BMC Medical Genetics, 2017-07-24)
    Background: We evaluated the associations between single nucleotide polymorphisms and different clinical parameters related to type 2 diabetes mellitus (T2DM), obesity risk, and metabolic syndrome (MS) in a Kazakh cohort. ...
  • Epidemiology of Brucellosis and Genetic Diversity of Brucella abortus in Kazakhstan 
    Shevtsova, Elena; Shevtsov, Alexandr; Mukanov, Kasim; Filipenko, Maxim; Kamalova, Dinara; Sytnik, Igor; Syzdykov, Marat; Kuznetsov, Andrey; Akhmetova, Assel; Zharova, Mira; Karibaev, Talgat; Tarlykov, Pavel; Ramanculov, Erlan (Plos One, 2016-12-01)
    Brucellosis is a major zoonotic infection in Kazakhstan. However, there is limited data on its incidence in humans and animals, and the genetic diversity of prevalent strains is virtually unstudied. Additionally, there is ...
  • Genetic risk factors for restenosis after percutaneous coronary intervention in Kazakh population 
    Zholdybayeva, Elena V.; Talzhanov, Yerkebulan A.; Aitkulova, Akbota M.; Tarlykov, Pavel V.; Kulmambetova, Gulmira N.; Iskakova, Aisha N.; Dzholdasbekova, Aliya U.; Visternichan, Olga A.; Taizhanova, Dana Zh.; Ramanculov, Yerlan M. (Human Genomics, 2016)
    Background: After coronary stenting, the risk of developing restenosis is from 20 to 35 %. The aim of the present study is to investigate the association of genetic variation in candidate genes in patients diagnosed with ...
  • GIW and InCoB, two premier bioinformatics conferences in Asia with a combined 40 years of history 
    Schönbach, Christian; Horton, Paul; Yiu, Siu Ming; Tan, Tin Wee; Ranganathan, Shoba (BMC, 2015)
    Knowledge discovery in bioinformatics thrives on joint and inclusive efforts of stakeholders. Similarly, knowledge dissemination is expected to be more effective and scalable through joint efforts. Therefore, the International ...
  • InCoB2013 introduces Systems Biology as a major conference theme 
    Schönbach, Christian; Shen, Bairong; Tan, Tin Wee; Ranganathan, Shoba (BMC, 2013-09)
    The Asia-Pacific Bioinformatics Network (APBioNet) held the first International Conference on Bioinformatics (InCoB) in Bangkok in 2002 to promote North-South networking. Commencing as a forum for Asia-Pacific researchers ...
  • InCoB2014: Mining Biological Data From Genomics for Transforming Industry and Health 
    Schönbach, Christian; Tan, Tin Wee; Ranganathan, Shoba (BMC, 2014)
    The 13th International Conference on Bioinformatics (InCoB2014) was held for the first time in Australia, at Sydney, July 31-2 August, 2014. InCoB is the annual scientific gathering of the Asia-Pacific Bioinformatics Network ...
  • Polymorphisms in genes involved in the absorption, distribution, metabolism, and excretion of drugs in the Kazakhs of Kazakhstan 
    Iskakova, Aisha N.; Romanova, Aliya A.; Aitkulova, Akbota M.; Sikhayeva, Nurgul S.; Zholdybayeva, Elena V.; Ramanculov, Erlan M. (BMC Genetics, 2016-01-19)
    Background: Studies of genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are crucial to the development of therapeutics in clinical medicine. Such data provide information that may ...
  • Reverse the Resistance to PARP Inhibitors 
    Kim, Yevgeniy; Kim, Aleksei; Sharip, Ainur; Sharip, Aigul; Jiang, Juhong; Yang, Qing; Xie, Yingqiu (International Journal of Biological Sciences, 2017-02-17)
    One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating ...