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SALIVARY MICROBIOME IN PEDIATRIC AND ADULT CELIAC DISEASE

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dc.contributor.author Poddighe, Dimitri
dc.contributor.author Kushugulova, Almagul R.
dc.date.accessioned 2021-09-14T08:13:27Z
dc.date.available 2021-09-14T08:13:27Z
dc.date.issued 2021-02-17
dc.identifier.citation Poddighe D and Kushugulova A (2021) Salivary Microbiome in Pediatric and Adult Celiac Disease. Front. Cell. Infect. Microbiol. 11:625162. doi: 10.3389/fcimb.2021.625162 en_US
dc.identifier.uri http://nur.nu.edu.kz/handle/123456789/5768
dc.description.abstract The human salivary microbiota includes hundreds of bacterial species. Alterations in gut microbiota have been explored in Celiac Disease (CD), but fewer studies investigated the characteristics of salivary microbiome in these patients, despite the potential implications in its pathogenesis. Indeed, some recent studies suggested that the partial digestion of gluten proteins by some bacteria may affect the array of gluten peptides reaching the gut and the way by which those are presented to the intestinal immune system. The available clinical studies investigating the salivary microbiota in children and adults, are insufficient to make any reliable conclusion, even though some bacterial species/phyla differences have been reported between celiac patients and controls. However, the salivary microbiome could correlate better with the duodenal microbiota, than the fecal one. Therefore, further clinical studies on salivary microbiome by different and independent research groups and including different populations, are advisable in order to explore the usefulness of the salivary microbiome analysis and understand some aspects of CD pathogenesis with potential clinical and practical implications. en_US
dc.language.iso en en_US
dc.publisher Front. Cell. Infect. Microbiol. en_US
dc.rights Attribution-NonCommercial-ShareAlike 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/us/ *
dc.subject Type of access: Open Access en_US
dc.subject celiac disease en_US
dc.subject salivary microbiota en_US
dc.subject microbiome en_US
dc.subject children en_US
dc.subject adults en_US
dc.title SALIVARY MICROBIOME IN PEDIATRIC AND ADULT CELIAC DISEASE en_US
dc.type Article en_US
workflow.import.source science


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